Myricetin
作者：齊岳
發(fā)布時(shí)間：2023-09-05
08:51:55
點(diǎn)擊數(shù)：
產(chǎn)品名稱：Myricetin
產(chǎn)品描述：
| 植物來源 | 天然產(chǎn)物 > 楊梅科 > 楊梅屬 |
| 結(jié)構(gòu)類型 | 天然產(chǎn)物 > 類黃酮 |
| 產(chǎn)品描述 | Myricetin is a naturally-occurring flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants. Walnuts are a rich dietary source. It has been shown that myricetin has antioxidant properties. |
| 靶點(diǎn)活性 | PI3Kγ:0.17 μM(Kd) |
| 體內(nèi)活性 | Treatment of orthotopic pancreatic tumors with myricetin results in tumor regression and decreases metastatic spread[3]. |
| 細(xì)胞實(shí)驗(yàn) | Pancreatic cancer cells (MIA PaCa-2, Panc-1 or S2-013) or normal pancreatic ductal cells (PDCs) are treated with myricetin (12.5–200 μM). Cell viability is determined using the Dojindo Cell Counting Kit-8. Cells are seeded onto a 96-well plate at 1×104 cells per well and allowed to adhere overnight. After treatment with myricetin at various concentrations for 24 hours, 10 μL of the tetrazolium substrate is added to each well of the plate. Plates are incubated at 37°C for 1 hour, after which the absorbance at 450 nm is measured[2]. |
| 別名 | Cannabiscetin, 楊梅素 |
| 分子量 | 318.24 |
| 分子式 | C15H10O8 |
| CAS No. | 529-44-2 |
存儲(chǔ)
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
溶解度
Ethanol: 20 mg/mL (62.84 mM),warmed
DMSO: 63 mg/mL (197.96 mM)
( < 1 mg/mL refers to the product slightly soluble or insoluble )
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