產(chǎn)品名稱：活性氧Cu/Zn SOD Monoclonal Antibody，Cu/Zn Superoxide Dismutase

產(chǎn)品描述：

產(chǎn)品名稱：

活性氧Cu/Zn SOD Monoclonal Antibody，Cu/Zn Superoxide Dismutase

產(chǎn)地：西安

規(guī)格：1mg 5mg 10mg

純度：99%

用途：僅用于科研

狀態(tài)：固體/粉末

儲藏條件：冷藏-20℃

溫馨提示：僅用于科研，不能用于人體實驗！

說明：提供使用說明，核磁圖譜，包裝，價格，產(chǎn)地，制備方法，應用，穩(wěn)定性，溶解度，簡單合成等各種信息　　

Cu/Zn Superoxide dismutase (Cu/Zn SOD) is an antioxidant enzyme that protects cells from oxidative stress by scavenging superoxide anions.1 It exists as a homodimer that is stabilized by a disulfide bond between the subunits. Each monomer is composed of a Greek key β-barrel and an active site channel made up of a β4/β5 loop, which interacts with the dimer interface and active site zinc, and an electrostatic loop, which facilitates superoxide entry into the copper-containing active site.2 Cu/Zn SOD is ubiquitously expressed and primarily localizes to the cytosol but has also been found in the nucleus, peroxisomes, lysosomes, and the intermembrane space of mitochondria.3,4 It catalyzes the dismutation of superoxide to hydrogen peroxide and oxygen by alternating reduction and reoxidation of copper at the enzyme active site.1 Overexpression of SOD1 protects against increases in reactive oxygen species (ROS) and apoptosis in an in vitro model of renal ischemia induced by ATP depletion.5 In vivo, transgenic mice expressing the destabilized Cu/Zn SODG93A mutation exhibit impaired spinal cord mitochondrial respiration.6,7 Mutations in SOD1 are associated with amyotrophic lateral sclerosis (ALS).8 Cayman’s Cu/Zn SOD Monoclonal Antibody can be used for flow cytometry (FC), immunoprecipitation (IP), and Western blot (WB) applications.

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編輯：XAQYBIO HAO，2023年3月27日。

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公司介紹：

西安齊岳生物科技有限公司是集化學科研和定制與一體的高科技化學公司。業(yè)務范圍包括化學試劑和產(chǎn)品的研發(fā)、生產(chǎn)、銷售等。涉及產(chǎn)品為通用試劑的分銷、非通用試劑的定制與研發(fā)，涵蓋生物科技、化學品、中間體和化工材料等領域。
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