產(chǎn)品名稱：活性氧Nitrotyrosine (Peptide) Polyclonal Antibody，3-Nitrotyrosine

產(chǎn)品描述：

產(chǎn)品名稱：

活性氧Nitrotyrosine (Peptide) Polyclonal Antibody，3-Nitrotyrosine

產(chǎn)地：西安

規(guī)格：1mg 5mg 10mg

純度：99%

用途：僅用于科研

狀態(tài)：固體/粉末

儲藏條件：冷藏-20℃

溫馨提示：僅用于科研，不能用于人體實驗！

說明：提供使用說明，核磁圖譜，包裝，價格，產(chǎn)地，制備方法，應用，穩(wěn)定性，溶解度，簡單合成等各種信息　　

Nitrotyrosine is a post-translational modification that is formed by the nitration of tyrosine.1 Under conditions of oxidative stress, tyrosine is oxidized by reactive oxygen species (ROS) or, in the presence of hydrogen peroxide and nitrite, by myeloperoxidase (MPO) to yield a tyrosine radical that reacts with reactive nitrogen species (RNS), such as nitric oxide or peroxynitrite, to form nitrotyrosine. It exists in a free or protein-bound form and is commonly used as a marker of nitrosative or oxidative stress.2 Nitrotyrosine residues have been found in a variety of proteins, including LDL, surfactant protein A, angiotensin II, and human and bovine serum albumin.3 Free nitrotyrosine production induced by peroxynitrite is inhibited by the polyphenols epicatechin gallate, gallic acid, catechin, or epicatechin in cell-free assays, as well as in aortic rings isolated from normotensive and spontaneously hypertensive rats administered the antioxidant N-acetyl-cysteine (NAC; Item No. 20261).4,5 Nitrotyrosine levels are increased in the affected tissues of numerous pathological conditions, including atherosclerosis, cancer, ulcerative colitis, Alzheimer's disease, and Parkinson's disease.3 Autoantibodies that recognize nitrotyrosinated proteins are increased in the synovium of patients with rheumatoid arthritis and are positively correlated with joint and tendon inflammation.1 Cayman's Nitrotyrosine (Peptide) Polyclonal Antibody has been prepared by affinity purification to exclude non-nitrotyrosine antibodies generated against the antigenic peptide backbone. This antibody can be used for Western blot (WB) applications.

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編輯：XAQYBIO HAO，2023年3月27日。

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西安齊岳生物科技有限公司是集化學科研和定制與一體的高科技化學公司。業(yè)務范圍包括化學試劑和產(chǎn)品的研發(fā)、生產(chǎn)、銷售等。涉及產(chǎn)品為通用試劑的分銷、非通用試劑的定制與研發(fā)，涵蓋生物科技、化學品、中間體和化工材料等領(lǐng)域。
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