CAS:4004-05-1 DOPE 1,2-二油酰-SN-甘油-3-磷酰乙醇胺
產(chǎn)品名稱:CAS:4004-05-1 DOPE 1,2-二油酰-SN-甘油-3-磷酰乙醇胺
產(chǎn)品描述:
別名 1,2-二油酰-SN-甘油-3-磷酰乙醇胺
DOPE
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 是一種陽(yáng)離子脂質(zhì)體的中性輔助脂質(zhì) (helper Lipid),能夠與陽(yáng)離子磷脂結(jié)合,增強(qiáng)裸 siRNA 的轉(zhuǎn)染效率。
產(chǎn)品描述 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.

靶點(diǎn)活性 helper lipid for liposome:
體外活性 Each siRNA is encapsulated in LNP (cationic lipid-A: PEG2000-DMPE: DOPE = 47.8: 5.18: 47.1 molar percent). With the neutral lipid for the LNP is DOPE, LNP exerts knock-down (KD) effect on macrophages and DCs and Liposome-containing DOPE shows fusogenicity. LNP/siRNA significantly suppresses CD45 protein expression at an inhibition rate of 30% on macrophages and DCs but not on monocytes, neutrophils, plasmacytoid DCs, or B cells.
包裝:瓶裝
供應(yīng)商:西安齊岳生物科技
產(chǎn)地:西安
溫馨提示:本產(chǎn)品僅用于科研實(shí)驗(yàn)
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